SERS enables direct and rapid trace level detection for toxins, viruses, bacteria, cancer, DNA and RNA at clinical sites.
Raman spectra could be detected from 20 μL of 10 μM R6G sprinkled onto glass coated with silver nanowires as SERS. Without SERS, 10 μM R6G couldn't be detected.
3D RCW SERS improves the discriminant accuracy.
With the 3D random crossed wire woodpile (RCW) used as a SERS chip for direct and rapid detection of pesticides (a) thiram, (b) carbaryl, (c) paraquat, and (d) fipronil with rational detecting ranges (nanomole), the discriminant accuracy of Raman spectra is improved.
« A 3D Plasmonic Crossed-Wire Nanostructure for Surface-Enhanced Raman Scattering and Plasmon-Enhanced Fluorescence Detection »
Tip enhanced Raman spectroscopy (TERS), making use of the « hot spot » effect created by the nano-scale tip apex, could further enhance Raman signals in addition to SERS, increasing both the detection sensitivity and mapping resolution.
Our STM tip enhanced Raman spectrometer will be released in 2022.