SERS enables direct and rapid trace level detection for toxins, viruses, bacteria, cancer, antibody, DNA and RNA at clinical sites, without the need of preprocessing of blood or other samples.
Raman spectra could be detected from 20 μL of 10 μM R6G sprinkled onto glass coated with silver nanowires as SERS. However, the same 10 μM R6G couldn't be detected without the use of SERS.
3D RCW SERS improves the discriminant accuracy.
With the 3D random crossed wire woodpile (RCW) used as a SERS chip for direct and rapid detection of pesticides (a) thiram, (b) carbaryl, (c) paraquat, and (d) fipronil with rational detecting ranges (nanomole), the discriminant accuracy of Raman spectra is improved.
« A 3D Plasmonic Crossed-Wire Nanostructure for Surface-Enhanced Raman Scattering and Plasmon-Enhanced Fluorescence Detection »
Tip enhanced Raman spectroscopy (TERS), enhances Raman signals of nanoscale structures or trace elements, through the « hot spot » effect created by the nano-scale tip apex. TERS with STM also enables the mapping resolution to go below 100 nm.
Our tip enhanced Raman spectrometer with STM will be released in 2022. The inline and high vacuum TERS system will be available in 2023, as well as the AFM and SNOM modules integrated in the same TERS system.